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rhil 17c  (R&D Systems)


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    R&D Systems rhil 17c
    Effect of <t>IL-17C</t> on malignant transformation in IL-17RE knockdown and overexpressed endometriotic cells (A) qPCR and western blot assay were used to measure the transfection efficiency and IL-17RE expression of si-IL-17RE in 11Z and 12Z. (B) Immunofluorescence staining reveals the effect <t>of</t> <t>rhIL-17C</t> on the expression of PCNA in IL-17RE knockdown 11Z and 12Z. (C–E) (C) Colony formation, (D) adhesion, and (E) migration and invasion were detected in parallel 11Z and 12Z cultures. (F and G) Western blot analysis was used to detect the expression of EMT-related and PI3K pathway key proteins in IL-17RE knockdown cells with or without rhIL-17C for 24 h. (H–J) (H) Immunohistological staining of PCNA, (I) colony formation, and (J) migration and invasion was detected in IL-17RE-overexpressing 11Z and 12Z with and without MOR106 treatment for 24 h. (K) Western blot analysis was used to detect the expression of EMT-related and (L) PI3K pathway key proteins in 11Z and 12Z with and without MOR106 treatment. n = 3 biological replicates. Data are represented as mean ± SEM. ∗ p < 0.05 and ∗∗ p < 0.01 for the indicated comparisons. Differences between groups were assessed using one-way ANOVA with Tukey’s post-hoc test. ns, not significant. Scale bars, 100 μm.
    Rhil 17c, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 11 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rhil 17c/product/R&D Systems
    Average 94 stars, based on 11 article reviews
    rhil 17c - by Bioz Stars, 2026-06
    94/100 stars

    Images

    1) Product Images from "Therapeutic targeting of interleukin-17C signaling in carcinogenesis of endometriosis"

    Article Title: Therapeutic targeting of interleukin-17C signaling in carcinogenesis of endometriosis

    Journal: Cell Reports Medicine

    doi: 10.1016/j.xcrm.2025.102464

    Effect of IL-17C on malignant transformation in IL-17RE knockdown and overexpressed endometriotic cells (A) qPCR and western blot assay were used to measure the transfection efficiency and IL-17RE expression of si-IL-17RE in 11Z and 12Z. (B) Immunofluorescence staining reveals the effect of rhIL-17C on the expression of PCNA in IL-17RE knockdown 11Z and 12Z. (C–E) (C) Colony formation, (D) adhesion, and (E) migration and invasion were detected in parallel 11Z and 12Z cultures. (F and G) Western blot analysis was used to detect the expression of EMT-related and PI3K pathway key proteins in IL-17RE knockdown cells with or without rhIL-17C for 24 h. (H–J) (H) Immunohistological staining of PCNA, (I) colony formation, and (J) migration and invasion was detected in IL-17RE-overexpressing 11Z and 12Z with and without MOR106 treatment for 24 h. (K) Western blot analysis was used to detect the expression of EMT-related and (L) PI3K pathway key proteins in 11Z and 12Z with and without MOR106 treatment. n = 3 biological replicates. Data are represented as mean ± SEM. ∗ p < 0.05 and ∗∗ p < 0.01 for the indicated comparisons. Differences between groups were assessed using one-way ANOVA with Tukey’s post-hoc test. ns, not significant. Scale bars, 100 μm.
    Figure Legend Snippet: Effect of IL-17C on malignant transformation in IL-17RE knockdown and overexpressed endometriotic cells (A) qPCR and western blot assay were used to measure the transfection efficiency and IL-17RE expression of si-IL-17RE in 11Z and 12Z. (B) Immunofluorescence staining reveals the effect of rhIL-17C on the expression of PCNA in IL-17RE knockdown 11Z and 12Z. (C–E) (C) Colony formation, (D) adhesion, and (E) migration and invasion were detected in parallel 11Z and 12Z cultures. (F and G) Western blot analysis was used to detect the expression of EMT-related and PI3K pathway key proteins in IL-17RE knockdown cells with or without rhIL-17C for 24 h. (H–J) (H) Immunohistological staining of PCNA, (I) colony formation, and (J) migration and invasion was detected in IL-17RE-overexpressing 11Z and 12Z with and without MOR106 treatment for 24 h. (K) Western blot analysis was used to detect the expression of EMT-related and (L) PI3K pathway key proteins in 11Z and 12Z with and without MOR106 treatment. n = 3 biological replicates. Data are represented as mean ± SEM. ∗ p < 0.05 and ∗∗ p < 0.01 for the indicated comparisons. Differences between groups were assessed using one-way ANOVA with Tukey’s post-hoc test. ns, not significant. Scale bars, 100 μm.

    Techniques Used: Transformation Assay, Knockdown, Western Blot, Transfection, Expressing, Immunofluorescence, Staining, Migration



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    rhil 17c  (R&D Systems)
    94
    R&D Systems rhil 17c
    Effect of <t>IL-17C</t> on malignant transformation in IL-17RE knockdown and overexpressed endometriotic cells (A) qPCR and western blot assay were used to measure the transfection efficiency and IL-17RE expression of si-IL-17RE in 11Z and 12Z. (B) Immunofluorescence staining reveals the effect <t>of</t> <t>rhIL-17C</t> on the expression of PCNA in IL-17RE knockdown 11Z and 12Z. (C–E) (C) Colony formation, (D) adhesion, and (E) migration and invasion were detected in parallel 11Z and 12Z cultures. (F and G) Western blot analysis was used to detect the expression of EMT-related and PI3K pathway key proteins in IL-17RE knockdown cells with or without rhIL-17C for 24 h. (H–J) (H) Immunohistological staining of PCNA, (I) colony formation, and (J) migration and invasion was detected in IL-17RE-overexpressing 11Z and 12Z with and without MOR106 treatment for 24 h. (K) Western blot analysis was used to detect the expression of EMT-related and (L) PI3K pathway key proteins in 11Z and 12Z with and without MOR106 treatment. n = 3 biological replicates. Data are represented as mean ± SEM. ∗ p < 0.05 and ∗∗ p < 0.01 for the indicated comparisons. Differences between groups were assessed using one-way ANOVA with Tukey’s post-hoc test. ns, not significant. Scale bars, 100 μm.
    Rhil 17c, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rhil 17c/product/R&D Systems
    Average 94 stars, based on 1 article reviews
    rhil 17c - by Bioz Stars, 2026-06
    94/100 stars
    		  Buy from Supplier
    rhil-17c  (Thermo Fisher)
    90
    Thermo Fisher rhil-17c
    Effect of <t>IL-17C</t> on malignant transformation in IL-17RE knockdown and overexpressed endometriotic cells (A) qPCR and western blot assay were used to measure the transfection efficiency and IL-17RE expression of si-IL-17RE in 11Z and 12Z. (B) Immunofluorescence staining reveals the effect <t>of</t> <t>rhIL-17C</t> on the expression of PCNA in IL-17RE knockdown 11Z and 12Z. (C–E) (C) Colony formation, (D) adhesion, and (E) migration and invasion were detected in parallel 11Z and 12Z cultures. (F and G) Western blot analysis was used to detect the expression of EMT-related and PI3K pathway key proteins in IL-17RE knockdown cells with or without rhIL-17C for 24 h. (H–J) (H) Immunohistological staining of PCNA, (I) colony formation, and (J) migration and invasion was detected in IL-17RE-overexpressing 11Z and 12Z with and without MOR106 treatment for 24 h. (K) Western blot analysis was used to detect the expression of EMT-related and (L) PI3K pathway key proteins in 11Z and 12Z with and without MOR106 treatment. n = 3 biological replicates. Data are represented as mean ± SEM. ∗ p < 0.05 and ∗∗ p < 0.01 for the indicated comparisons. Differences between groups were assessed using one-way ANOVA with Tukey’s post-hoc test. ns, not significant. Scale bars, 100 μm.
    Rhil 17c, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rhil-17c/product/Thermo Fisher
    Average 90 stars, based on 1 article reviews
    rhil-17c - by Bioz Stars, 2026-06
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    Effect of IL-17C on malignant transformation in IL-17RE knockdown and overexpressed endometriotic cells (A) qPCR and western blot assay were used to measure the transfection efficiency and IL-17RE expression of si-IL-17RE in 11Z and 12Z. (B) Immunofluorescence staining reveals the effect of rhIL-17C on the expression of PCNA in IL-17RE knockdown 11Z and 12Z. (C–E) (C) Colony formation, (D) adhesion, and (E) migration and invasion were detected in parallel 11Z and 12Z cultures. (F and G) Western blot analysis was used to detect the expression of EMT-related and PI3K pathway key proteins in IL-17RE knockdown cells with or without rhIL-17C for 24 h. (H–J) (H) Immunohistological staining of PCNA, (I) colony formation, and (J) migration and invasion was detected in IL-17RE-overexpressing 11Z and 12Z with and without MOR106 treatment for 24 h. (K) Western blot analysis was used to detect the expression of EMT-related and (L) PI3K pathway key proteins in 11Z and 12Z with and without MOR106 treatment. n = 3 biological replicates. Data are represented as mean ± SEM. ∗ p < 0.05 and ∗∗ p < 0.01 for the indicated comparisons. Differences between groups were assessed using one-way ANOVA with Tukey’s post-hoc test. ns, not significant. Scale bars, 100 μm.

    Journal: Cell Reports Medicine

    Article Title: Therapeutic targeting of interleukin-17C signaling in carcinogenesis of endometriosis

    doi: 10.1016/j.xcrm.2025.102464

    Figure Lengend Snippet: Effect of IL-17C on malignant transformation in IL-17RE knockdown and overexpressed endometriotic cells (A) qPCR and western blot assay were used to measure the transfection efficiency and IL-17RE expression of si-IL-17RE in 11Z and 12Z. (B) Immunofluorescence staining reveals the effect of rhIL-17C on the expression of PCNA in IL-17RE knockdown 11Z and 12Z. (C–E) (C) Colony formation, (D) adhesion, and (E) migration and invasion were detected in parallel 11Z and 12Z cultures. (F and G) Western blot analysis was used to detect the expression of EMT-related and PI3K pathway key proteins in IL-17RE knockdown cells with or without rhIL-17C for 24 h. (H–J) (H) Immunohistological staining of PCNA, (I) colony formation, and (J) migration and invasion was detected in IL-17RE-overexpressing 11Z and 12Z with and without MOR106 treatment for 24 h. (K) Western blot analysis was used to detect the expression of EMT-related and (L) PI3K pathway key proteins in 11Z and 12Z with and without MOR106 treatment. n = 3 biological replicates. Data are represented as mean ± SEM. ∗ p < 0.05 and ∗∗ p < 0.01 for the indicated comparisons. Differences between groups were assessed using one-way ANOVA with Tukey’s post-hoc test. ns, not significant. Scale bars, 100 μm.

    Article Snippet: Moreover, the effects of rhIL-17C (1234-IL-025, R&D Systems), anti-IL-17RE (NEUT-1237CQ, Creative biolabs, USA), MOR106 (BR2010231, Shanghai bioleaper biotechnology Co. Ltd., China) and LY294002 (HY-10108, MCE) were evaluated on cells respectively.

    Techniques: Transformation Assay, Knockdown, Western Blot, Transfection, Expressing, Immunofluorescence, Staining, Migration